Synlett
DOI: 10.1055/a-1499-8679
synpacts

Photoredox Enabled Decarboxylative Synthesis of Unnatural α-Amino Acids

Andrey Shatskiy
1  Department of Chemistry, Kungliga Tekniska Högskolan, Stockholm, Sweden (Ringgold ID: RIN7655)
,
2  Department of Chemistry, Kungliga Tekniska Hogskolan, Stockholm, Sweden (Ringgold ID: RIN7655)
› Author Affiliations


Recently, development of general synthetic routes to unnatural α-amino acids has gained a significant momentum, driven by the high demand for such building blocks in fundamental research within molecular and structural biology, as well as for development of new pharmaceuticals. Herein, we highlight the recent progress in employing photoredox-mediated synthetic methods for accessing unnatural α-amino acids with a focus on various decarboxylative radical-based strategies.



Publication History

Received: 08 April 2021

Accepted after revision: 05 May 2021

Publication Date:
05 May 2021 (online)

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