Synthesis 2022; 54(05): 1250-1260
DOI: 10.1055/a-1678-8528
short review

Organic Isocyanates and Isothiocyanates: Versatile Intermediates in Agrochemistry


In recent decades, organic isocyanates and isothiocyanates have been often applied as reactive intermediates in research syntheses or manufacturing routes of many agrochemicals. These heterocumulenes allowed the installation of crucial carboxylic functions, such as carbamates, ureas, and semicarbazones, but have also been used for the construction of five- and six-membered heterocycles, such as tetrazolones, thiazoles, and uracils.

1 Introduction

2 Preparation of Carboxylic Acid Functions

3 Preparation of Heterocyclic Rings

4 Conclusion

Publication History

Received: 27 September 2021

Accepted after revision: 26 October 2021

Publication Date:
26 October 2021 (online)

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