Abstract
Preparative thin-layer chromatography (prepTLC) is a commonly used method of purification
suitable for small-scale reactions. However, descriptions of the preferred methodology
to load, run, and recover samples from prepTLC are non-standard and varied, making
it part of the ‘hidden curriculum’ of laboratory techniques. In this article we report
on the simple, cost-effective methods we use to load and collect samples from a plate,
which enhance the convenience, speed, and precision of this technique.
Key words
laboratory technique - chromatography - separation science - thin-layer chromatography
- tools