Facile Access to α-Substituted β-Thio Enals from 1,2,3-Triazines and Thiols

Abstract

Herein, a chemoselective cascade addition reaction is reported, which starts from 1,2,3-triazines and thiols to access several different α-substituted β-thio enals and their derivatives in a green and efficient synthesis. In terms of applications, readily available substrates, diversity of products, and mild reaction system make this strategy highly attractive.

Key words

1,2,3-triazines - thiols - cascade reaction - thiolation - enals

• References

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