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Synthesis
DOI: 10.1055/a-2705-4304
DOI: 10.1055/a-2705-4304
Paper
Published as part of the Special Topic Dedicated to Prof. Paul Knochel
Photoinduced Deaminative C(sp3)–H Bond diarylation of glycine derivatives by cerium catalysis
Authors
This work was financial support from the National Natural Science Foundation of China (22171220); Fundamental Research Funds for the Central Universities (xtr072022003), and Natural Science Basic Research Plan in Shaanxi Province of China (2022JQ-130).
Abstract
A Ce(III)-catalyzed, visible light–induced aerobic oxidative diarylation of glycine derivatives with electron-rich aromatics is described. This method enables the efficient and rapid synthesis of diarylmethane derivatives under mild conditions, using air as the oxidant and obviating the need for an external photosensitizer. It is noteworthy that this protocol can be scaled up to 5 mmol without a significant impact on the efficiency.
Keywords
Glycine derivative - Visible-light induced - Photosensitizers free - Diarylation - Cerium catalysisPublication History
Received: 10 July 2025
Accepted after revision: 02 September 2025
Accepted Manuscript online:
19 September 2025
Article published online:
10 October 2025
© 2025. Thieme. All rights reserved.
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