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DOI: 10.1055/a-2705-6689
Efficient oxidation of internal alkynes to 1,2-diketone compounds catalyzed by a binuclear ruthenium complex
Gefördert durch: Fundamental Research Funds for the Central Universities DUT22LAB612,DUT24ZD132
Gefördert durch: National Natural Science Foundation of China 22172014,22372024
Gefördert durch: Foundation of Guizhou Educational Committee qianjiaoji [2023] 088
Gefördert durch: “Excellence Co-Innovation Program” International Exchange Fund Project DUTIO-ZG-202505

Structurally methane monooxygenase (MMO) active site-like new binuclear ruthenium complex-catalyzed oxidation of internal alkynes is described. The direct catalytic oxidation of internal alkynes proceeded smoothly and completed within 15 minutes in the presence of NaIO4 as the oxidant to produce 1,2-diketone products in high to excellent yields. The binuclear ruthenium complex can be easily prepared and handled, and which has high catalytic activity (TOFmax = 5778 h-1) and a long lifetime (TONmax = 52000). Various synthetically useful functional groups, such as halogen atoms, acetyl, and TMS, remain intact during the oxidation of internal alkynes.
Publikationsverlauf
Eingereicht: 13. Juli 2025
Angenommen nach Revision: 02. September 2025
Accepted Manuscript online:
19. September 2025
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