5-Alkylsulfonyl-1H-tetrazoles: Oxidizers and Catalysts for the Oxidation of Sulfides to Sulfoxides with Hydrogen Peroxide

Abstract

A new preparative method for the oxidation of sulfides to their corresponding sulfoxides using hydrogen peroxide in the presence of 5-alkylsulfonyl-1H-tetrazoles has been proposed. The method demonstrates high efficiency for sulfides with aliphatic, aromatic, and heterocyclic substituents. The role of 5-alkylsulfonyl-1H-tetrazoles in the oxidative process has been demonstrated.

Keywords

Organocatalytic oxidation - Sulfoxides - Sulfides - Hydrogen peroxide - 5-Alkylsulfonyl-1H-tetrazoles

Publication History

Received: 10 September 2025

Accepted after revision: 28 November 2025

Article published online:
22 December 2025

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