Planar Chiral Sulfur Compound Derived from [2.2]Paracyclophane: Synthesis and Applications

Abstract

Over the past decade, planar chiral sulfur-containing [2.2]paracyclophanes have attracted increasing attention. This review offers a comprehensive overview of the strategies developed to access these appealing derivatives, along with their diverse applications in fields ranging from catalysis to materials science. The discussion is organized according to the type and position of the sulfur functional group within the [2.2]paracyclophane framework.

Keywords

Cyclophanes - Sulfur - Chirality - Stereoselective synthesis - Thiols - Sulfoxides - Thiophenes - Sulfides

Publication History

Received: 26 September 2025

Accepted after revision: 03 December 2025

Article published online:
30 December 2025

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