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Formal Synthesis of (-)-Platencin
K. Tiefenbacher*, J. Mulzer*
Universität Wien, Austria
22 January 2009 (online)
Platencin was isolated from the microorganism Streptomyces platensis along with platensimycin. Both natural products have sparked a great deal of interest due to their impressive antibiotic properties, especially against drug resistant bacterial strains. This paper details a short and simple route to the polycyclic head of platencin.