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Synfacts 2010(1): 0004-0004  
DOI: 10.1055/s-0029-1218401
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Antibiotic TAN-1085

Contributor(s): Philip Kocienski
K. Mori, K. Ohmori, K. Suzuki*
Tokyo Institute of Technology, Japan
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Publikationsdatum:
21. Dezember 2009 (online)

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Significance

The synthesis of TAN-1085 by ­Suzuki and co-workers is notable for its consecutive relay of central and axial chirality elements in three chirality transfer steps: central → axial (A + B → C), axial → axial (F → G) and axial → central (H → I).