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Synlett 2012; 23(15): 2201-2204
DOI: 10.1055/s-0032-1316993
DOI: 10.1055/s-0032-1316993
letter
Titanium(IV) Isopropoxide as an Efficient Catalyst for Direct Amidation of Nonactivated Carboxylic Acids
Further Information
Publication History
Received: 25 May 2012
Accepted after revision: 03 July 2012
Publication Date:
17 August 2012 (online)
Abstract
Secondary and tertiary amides are formed in high yields, in an efficient and environmentally benign titanium(IV) isopropoxide catalyzed direct amidation of carboxylic acids with primary and secondary amines.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synlett.
- Supporting Information
-
References and Notes
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