Synlett 2015; 26(04): 421-425
DOI: 10.1055/s-0034-1379979
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© Georg Thieme Verlag Stuttgart · New York

Unprotected Carbohydrates as Starting Material in Chemical Synthesis: Not Just a Challenge but an Opportunity

Tiina Saloranta*
Laboratory of Organic Chemistry, Åbo Akademi University, Piispankatu 8, 20500 Turku, Finland   Email: tiina.saloranta@abo.fi
,
Reko Leino
Laboratory of Organic Chemistry, Åbo Akademi University, Piispankatu 8, 20500 Turku, Finland   Email: tiina.saloranta@abo.fi
› Author Affiliations
Further Information

Publication History

Received: 28 November 2014

Accepted after revision: 17 December 2014

Publication Date:
03 February 2015 (online)

Abstract

Development of reaction sequences that utilize renewable resources, such as carbohydrates, as starting material is of topical interest. Particularly attractive are reaction protocols where unprotected mono- and oligosaccharides are applied. Herein, selected approaches for direct derivatization of unprotected carbohydrates are highlighted. Ultimately, such methodologies are also applicable for natural polysaccharides resulting in rapid development of novel functional biobased materials for future applications.

1 Introduction

2 Reacting Unprotected Carbohydrates as Aldehydes

3 Approaches for Selective Reactions Targeting the Nonanomeric Hydroxyl Groups on Unprotected Carbohydrates

4 Protecting-Group-Free Synthesis of Glycoclusters and Glycoconjugates

5 Conclusions

 
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