Palladium-Catalyzed ortho-Acylation of 2-Aryl-1,2,3-triazoles with Toluene Derivatives

Abstract

A palladium-catalyzed ortho-acylation of 2-aryl-1,2,3-triazoles was developed in which low-toxicity, stable, commercially available toluene derivatives were used as acyl sources. A wide variety of aryl ketones containing 1,2,3-triazoles were obtained in moderate to excellent yields. A plausible mechanism is proposed.

Key words

palladium - catalysis - acylations - triazoles - ketones

• References

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