Synthesis, Table of Contents Synthesis 2015; 47(09): 1309-1316DOI: 10.1055/s-0034-1380401 paper © Georg Thieme Verlag Stuttgart · New York Palladium-Catalyzed ortho-Acylation of 2-Aryl-1,2,3-triazoles with Toluene Derivatives Ping He a Department of Chemistry, Tongji University, Siping Road 1239, Shanghai 200092, P. R. of China Email: kuangcx@tongji.edu.cn , Qingshan Tian a Department of Chemistry, Tongji University, Siping Road 1239, Shanghai 200092, P. R. of China Email: kuangcx@tongji.edu.cn , Chunxiang Kuang* a Department of Chemistry, Tongji University, Siping Road 1239, Shanghai 200092, P. R. of China Email: kuangcx@tongji.edu.cn b Key Laboratory of Yangtze River Water Environment, Ministry of Education, Siping Road 1239, Shanghai 200092, P. R. of China › Author Affiliations Recommend Article Abstract Buy Article All articles of this category Abstract A palladium-catalyzed ortho-acylation of 2-aryl-1,2,3-triazoles was developed in which low-toxicity, stable, commercially available toluene derivatives were used as acyl sources. A wide variety of aryl ketones containing 1,2,3-triazoles were obtained in moderate to excellent yields. A plausible mechanism is proposed. Key words Key wordspalladium - catalysis - acylations - triazoles - ketones Full Text References References 1a Zhao D, You J, Hu C. Chem. Eur. J. 2011; 17: 5466 1b Giri R, Shi B.-F, Engle KM, Maugel N, Yu J.-Q. Chem. Soc. Rev. 2009; 38: 3242 1c Engle KM, Mei T.-S, Wasa M, Yu J.-Q. Acc. Chem. Res. 2012; 45: 788 1d McMurray L, O’Hara F, Gaunt MJ. Chem. Soc. Rev. 2011; 40: 1885 1e Muller P, Fruit C. Chem. Rev. 2003; 103: 2905 1f Lewis JC, Bergman RG, Ellman JA. Acc. Chem. Res. 2008; 41: 1013 1g Yeung CS, Dong VM. Chem. 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