Small Is (also) Beautiful: Dynamic Covalent Self-Assembly of Cryptates
Received: 06 August 2015
Accepted: 14 August 2015
03 September 2015 (eFirst)
Cryptands can be seen as the smallest three-dimensional molecular cages still capable of accommodating (ionic) guests. We have recently realized the first dynamic covalent self-assembly of a monometallic cryptate, whose template synthesis and unique structure crucially rest on orthoester bridgeheads [Nat. Commun. 2015, 6, 7129]. In this Synpacts article, I discuss selected aspects that led to this discovery and I attempt to put the study into the context of recent trends in the self-assembly of larger molecular cages.
2 Dynamic Covalent Self-Assembly of Orthoester Cryptates
3 From Covalent to Metallosupramolecular to Dynamic Covalent Synthesis
4 Orthoester Cryptates as Tiny Self-Assembled Cages