KI/K2S2O8-Mediated α-C–H Sulfenylation of Carbonyl Compounds with (Hetero)Aryl ThiolsThis work was supported by National Natural Science Foundation of China (No. 21476068, 21471053), Innovation Platform Project of Education Bureau of Hunan Province, China (No. 13K101), and Hunan Provincial Innovation Foundation for Postgraduate (No. CX2016B669).
Received: 04 April 2017
Accepted after revision: 04 June 2017
13 July 2017 (eFirst)
A new and facile KI/K2S2O8-mediated α-C–H sulfenylation of carbonyl compounds with (hetero)aryl thiols was developed for the formation of C–S bond at room temperature. This method provided a simple process for the synthesis of β-keto thioethers in moderate to excellent yields. A variety of carbonyl compounds and (hetero)aryl thiols were tolerated in this reaction.