Highly Selective Approach to α-Iodoketones from Aminoalkynols with Iodine Monochloride
Received: 22 July 2017
Accepted after revision: 04 August 2017
31 August 2017 (eFirst)
A protocol has been developed to achieve selective and direct synthesis of α-iodoketones under mild condition, from the reaction of aminoalkynols with iodine monochloride. The scope of the reaction was investigated using various aminoalkynols with iodine monochloride and the corresponding α-iodoketones were obtained selectively without forming iodocyclized and/or addition products.