Radical Allylation: E-Selective Radical Conjugate Addition–Elimination Reaction from Morita–Baylis–Hillman AdductsThis work was supported by the excellence laboratory LabEx SYNORG (ANR-11-LABX-0029), the Conseil Régional de Normandie, and the European FEDER fundings.
Received: 28 July 2017
Accepted after revision: 07 September 2017
27 September 2017 (eFirst)
Triethylborane-mediated radical allylation was performed from Morita–Baylis–Hillman alcohols with no need of protecting group. The radical conjugated addition–elimination reaction is highly selective, and trisubstituted E-alkenes were obtained. This reaction opened a new route for the preparation of functionalized α,β-unsaturated ketones.