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Synthesis 2019; 51(12): 2484-2488
DOI: 10.1055/s-0037-1611800
DOI: 10.1055/s-0037-1611800
psp
Practical Gram-Scale Synthesis of Either α- or β-Anomer of C-Vinyl Glycosides
This work was supported by the Région des Pays de la Loire through the GlycoOuest program and the Ministère de l’Enseignement Supérieur et de la Recherche of France [Ph.D. fellowship (F.R.)].Further Information
Publication History
Received: 15 February 2019
Accepted after revision: 22 March 2019
Publication Date:
15 April 2019 (online)
Abstract
The synthesis C-vinyl glycosides, useful intermediates for the synthesis of C-glycoconjugates, was carried out on gram-scale by controlled reduction of the corresponding ethynyl derivatives in good to excellent yields in different carbohydrate series.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1611800.
- Supporting Information
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For example, see:
Benzyl protection:
Methyl protection:
In glucosamine series, see, for example: