First Example of Aryl–Hetaryl Cross-Coupling via [5,5]-Sigmatropic Rearrangement

Abstract

Polysubstituted furans and thiophenes with orthogonal functional groups were synthesized by a Strecker-type reaction leading to (arylaminonitriles), which underwent a [5,5]-sigmatropic rearrangement under mild conditions. The intramolecular character of the rearrangement was additionally proved.

Key words

heterocycles - aminonitriles - sigmatropic rearrangement - furans - thiophenes - thiazoles

Publikationsverlauf

Eingereicht: 04. Mai 2024

Angenommen nach Revision: 28. August 2024

Artikel online veröffentlicht:
26. September 2024

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