Indium(III) Complex-Catalyzed Tandem Carbonyl-Ene Reaction: An Efficient Construction of Tetrahydropyran Rings

Teck-Peng Loh; Li-Chun Feng; Jian-Ying Yang

doi:10.1055/s-2002-28501

SPECIALTOPIC

Indium(III) Complex-Catalyzed Tandem Carbonyl-Ene Reaction: An Efficient Construction of Tetrahydropyran Rings

Teck-Peng Loh*^a, Li-Chun Feng^b, Jian-Ying Yang^a
^a Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543
Fax: +(65)7791691; e-Mail: Chmlohtp@nus.edu.sg;
^b Institute of Chemical Science, Ayer Rajah Crescent, Blk 28, 02-08, Singapore 139959

Abstract

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Abstract

An atom economic and efficient construction of tetrahydropyran rings using Indium triflate-catalyzed self-tandem carbonyl-ene, intramolecular (2,5) oxonium-ene cyclization between aldehydes and methylene cyclohexane is reported.

Key words

indium(III) complex - tandem - carbonyl-ene - tetrahydropyran

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References

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