Mining Sequence Space for Asymmetric Aminocatalysis: N-Terminal Prolyl-Peptides Efficiently Catalyze Enantioselective Aldol and Michael Reactions

Abstract

N-Terminal prolyl-peptides efficiently catalyze asymmetric aldol and Michael reactions between acetone and p-nitro­benzaldehyde or β-nitrostyrene, respectively.

Key words

organocatalysis - enamine catalysis - aminocatalysis - peptides

References

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