Synthesis 2005(11): 1829-1837  
DOI: 10.1055/s-2005-865362
PAPER
© Georg Thieme Verlag Stuttgart · New York

Chiral Succinate: A Precursor for Enantiomerically Pure β2-Amino Acids

Arvydas Stončius, Markus Nahrwold, Norbert Sewald*
Bielefeld University, Department of Chemistry, Universitätsstr. 25, 33615 Bielefeld, Germany
Fax: +49(521)1068094; e-Mail: norbert.sewald@uni-bielefeld.de;
Further Information

Publication History

Received 26 October 2004
Publication Date:
02 May 2005 (online)

Abstract

Five suitably protected enantiomerically pure β2-amino acids, homologues of proteinogenic α-amino acids, were synthesized from the common chiral precursor, tert-butyl succinyloxazol­idinone.

24

It was later confirmed by mass spectrometry of crude product: signals corresponding to double alkylation products were observed in MS (ESI).

25

Manuscript in preparation.