Synthesis 2005(15): 2606-2608  
DOI: 10.1055/s-2005-872162
SPECIALTOPIC
© Georg Thieme Verlag Stuttgart · New York

Montmorillonite K10 Catalyzed Nucleophilic Addition Reaction to Aldimines in Water

Takahiko Akiyama*, Keiichiro Matsuda, Kohei Fuchibe
Department of Chemistry, Faculty of Science, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo 171-8588, Japan
e-Mail: takahiko.akiyama@gakushuin.ac.jp;
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Publikationsverlauf

Received 14 June 2005
Publikationsdatum:
12. August 2005 (online)

Abstract

Montmorillonite K10 catalyzed Mannich-type reaction and hydrophosphonylation proceeded smoothly in water at room temperature to give β-amino esters and α-amino phosphonates, respectively, in good to high yields.