PDF herunterladen
Synfacts 2008(3): 0232-0232  
DOI: 10.1055/s-2008-1042665
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (-)-Batzelladine D

Contributor(s): Philip Kocienski, Stewart Eccles
P. A. Evans*, J. Qin, J. E. Robinson, B. Bazin
University of Liverpool, UK and Indiana University, Bloomington, USA
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
21. Februar 2008 (online)

    Lizenzen und Reprints

Significance

Batzelladine D is a marine alkaloid with no known biological activity; however, other members of the batzelladine family have varied activities and the synthesis of the batzelladine tricyclic core is an important goal. This synthesis makes good use of azides as masked amines and a radical cyclization to construct the five-membered ring.