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Planta Med 1980; 39(5): 77-80
DOI: 10.1055/s-2008-1074906
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Isolation and Characterization of Alkaloids from a New Chemotype of Thalictrum minus

H. Dutschewska1 , B. Dimov1 , N. Mollov1 , L. Evstatieva2
  • 1Institute of Organic Chemistry of the Bulgarian Academy of Sciences, Sofia, Bulgaria.
  • 2Institute of Botany of the Bulgarian Academy of Sciences, Sofia, Bulgaria.
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Publication History

Publication Date:
29 April 2008 (online)

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Abstract

Thalictrum minus L. populations of the South-East of Bulgaria (Topolov-grad) represent a distinct chemotype. They contain N-methylcanadine hydroxide as main alkaloid in the herb. The main alkaloid (I) is accompanied by O-methylthalmethine (II), thalmethine (III), thalicberine (IV), O-methylthalic-berine (V), berberine (VI), argemonine (VII), eschscholzidine (VIII), glaucine (IX) and thalipoline. (I) was observed for the first time in Bulgarian plants belonging to Th. minus. The pavine alkaloids (VII) and (VIII) have been detected for the first time in Th. minus. Thalipoline is assumed to be a new pavine alkaloid.

Key Word Index

Thalictrum minus - Ranunculaceae - Alkaloids - N-Methylcanadine Hydroxide - O-Methylthalmethine - Thalmethine - Thalicberine - O-Methylthalicberine - Berberine - Argemonine - Eschscholzidine - Glaucine and Thalipoline.