Abstract
Visible-light-induced palladium-mediated reactions have become a novel and promising
field in organic synthesis. This photocatalytic arsenal presents complementary features
towards traditional Pd chemistry, allowing the achievement of new and unique reactivities
by the generation of versatile Pd-radical hybrid species. These putative intermediates
can be produced by direct excitation of Pd complexes, together with organic radical
precursors. This review aims at describing recent advances regarding the combination
of Pd-based photocatalytic manifolds and radical generation in the functionalization
of important motifs in synthetic chemistry, encompassing detailed mechanistic descriptions
and relevant examples.
1 Introduction
2 Homolytic Cleavage of C–X Bonds
3 Cyclizations, Desaturations and Atom Transfer Reactions
4 Homolytic Cleavage of N–O Bonds
5 Generation through Diazo Compounds
6 Generation of Acyl Radicals
7 Generation of Ketyl Radicals
8 Conclusions
Key words
palladium - light-driven process - photocatalysis - hybrid radical species - light-induced
transition-metal catalysis
