Sulfonimidamides, featuring a hexavalent sulfur structure, are a class of key compounds
with broad application prospects in the fields of pharmaceuticals and agrochemicals.
However, their applications have been limited due to the lack of economically effective
synthetic methods. Utilizing the cost-effective and readily accessible sulfonyl chloride
as the initial reagent, this method involves the sequential formation of intermediates,
including sulfinamide and sulfonimidoyl chloride, culminating in the synthesis of
the sulfonylimidamide compounds. This approach yields sulfonimidamides in moderate
to good yields, thereby offering a viable synthetic route for the expanded application
of these important compounds.
Key words
one-pot strategy - sulfonimidamide - sulfonyl chloride - sulfinamide - sulfonimidoyl
chloride
