Planta Med 2009; 75(13): 1442-1447
DOI: 10.1055/s-0029-1185724
Natural Product Chemistry
Original Paper
© Georg Thieme Verlag KG Stuttgart · New York

Naphthalene Aglycones and Glycosides from the Australian Medicinal Plant, Dianella callicarpa

Daniel Anthony Dias1 , Claudio Andres Silva1 , Sylvia Urban1
  • 1School of Applied Sciences (Discipline of Applied Chemistry), RMIT University, Melbourne, Victoria, Australia
Further Information

Publication History

received January 13, 2009 revised April 23, 2009

accepted April 26, 2009

Publication Date:
25 May 2009 (online)

Abstract

The crude extract of the roots from the Australian medicinal plant Dianella callicarpa (Liliaceae) displayed significant antimicrobial and antiviral activities. This prompted a chemical investigation, resulting in the isolation of the new naphthalene glycoside, dianellose (10), together with dianellin (1), dianellidin (2), dianellinone (3), stellalderol (9) and 5-hydroxydianellin (11). The structures for compounds 1, 9 and 10 were secured by detailed spectroscopic analyses, while compounds 2, 3 and 11 were identified on the basis of comparisons to literature data. Whilst the chemistry of the genus Dianella has previously been investigated, we report the first isolation of stellalderol (9) from this genus, together with the chemical and biological evaluation of the callicarpa species. Biological evaluation of the isolated compounds established that 2 showed antiviral and mild antimicrobial properties and that compounds 1, 9 and 10 displayed moderate antitumour activities.

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Dr. Sylvia Urban

School of Applied Sciences (Discipline of Applied Chemistry)
RMIT University

GPO Box 2476 V

Melbourne

Victoria 3001

Australia

Phone: + 6 13 99 25 33 76

Fax: + 6 13 99 25 37 47

Email: sylvia.urban@rmit.edu.au

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