The rhodium-catalysed addition of chiral alkenylboron reagents
to prochiral α,β-unsaturated carbonyl acceptors
are demonstrated to proceed under ligand control. The highest activities were
obtained with chiral olefin ligands and the configuration of the new
stereocentre can be predicted by using established models.
alkenylboronate - conjugate addition - rhodium - catalysis - chiral olefin ligands