Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2011(12): 1337-1337
DOI: 10.1055/s-0031-1289364
DOI: 10.1055/s-0031-1289364
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag
Stuttgart ˙ New York
Manganese-Catalyzed Enantioselective cis-Dihydroxylation
T. W.-S. Chow, Y. Liu, C.-M. Che*
The University of Hong Kong, P. R. of China
Further Information
Publication History
Publication Date:
18 November 2011 (online)
Significance
The authors report a practical protocol for the asymmetric cis-dihydroxylation of electron-deficient alkenes with Oxone catalyzed by a manganese complex bearing a chiral tetradentate N4-donor ligand affording the cis-diols in good yields with moderate to high enantioselectivity. This transformation has been scaled up to 6.2 mmol.