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Synthesis 2012(1): 87-92  
DOI: 10.1055/s-0031-1289608
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Copper(II) Triflate Promoted One-Pot Synthesis of Coumarin-, Quinolone-, and Naphthalene-Annulated 2-Aminothiazoles under Ligand-Free Conditions

K. C. Majumdar*a,b, Nirupam Dea, Debankan Ghosha, Sudipta Ponraa, B. Roya
a Department of Chemistry, University of Kalyani, Kalyani 741235, W.B., India
b Department of Chemical Sciences, Tezpur University, Napaam 784028, Assam, India
e-Mail: kcm_ku@yahoo.co.in;
Further Information

Publication History

Received 12 September 2011
Publication Date:
15 November 2011 (online)

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Abstract

An efficient synthesis of new 2-aminothiazole-annulated compounds is described via copper(II) triflate promoted sequential condensation, arylation, and heterocyclization reactions in one step. The reaction is compatible with a variety of substrates providing efficient access to many biologically important skeletons in good yields.

Key words

copper triflate - multicomponent reaction - naphthothiazole - domino synthesis - carbon disulfide

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