Iridium-Catalyzed Synthesis of ω-Hydroxy Homoallylic Alcohols

Yasushi Obora; Takuya Sawaguchi; Keiko Tsubakimoto; Hiroshi Yoshida; Shinji Ogawa; Shintaro Hatanaka

doi:10.1055/s-0033-1338510

Synthesis, Table of Contents

Synthesis 2013; 45(15): 2115-2119
DOI: 10.1055/s-0033-1338510

special topic

Iridium-Catalyzed Synthesis of ω-Hydroxy Homoallylic Alcohols

Authors

Yasushi Obora*

Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 5648680, Japan Fax: +81(6)63394026 Email: obora@kansai-u.ac.jp
Takuya Sawaguchi

Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 5648680, Japan Fax: +81(6)63394026 Email: obora@kansai-u.ac.jp
Keiko Tsubakimoto

Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 5648680, Japan Fax: +81(6)63394026 Email: obora@kansai-u.ac.jp
Hiroshi Yoshida

Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 5648680, Japan Fax: +81(6)63394026 Email: obora@kansai-u.ac.jp
Shinji Ogawa

Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 5648680, Japan Fax: +81(6)63394026 Email: obora@kansai-u.ac.jp
Shintaro Hatanaka

Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita, Osaka 5648680, Japan Fax: +81(6)63394026 Email: obora@kansai-u.ac.jp

Abstract

All articles of this category

Abstract

A novel process has been developed for the construction ω-hydroxy homoallylic alcohols via the iridium-catalyzed reaction of α,ω-diols with 2-alkynes such as 1-arylprop-1-ynes.

Key words

iridium catalyst - ω-hydroxy homoallylic alcohol - diol - transfer hydrogenation - 1-arylprop-1-yne

Full Text

References

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Supplementary Material

Supporting Information (PDF)