Synthesis 2014; 46(23): 3133-3171
DOI: 10.1055/s-0034-1378672
review
© Georg Thieme Verlag Stuttgart · New York

Preparation of Functionalized Lithium, Magnesium, Aluminum, Zinc, Manganese­, and Indium Organometallics from Functionalized Organic Halides

Guillaume Dagousset
Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5‒13, 81377 Munich, Germany   Phone: +49(89)218077680   Email: Paul.Knochel@cup.uni-muenchen.de
,
Cyril François
Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5‒13, 81377 Munich, Germany   Phone: +49(89)218077680   Email: Paul.Knochel@cup.uni-muenchen.de
,
Thierry Leόn
Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5‒13, 81377 Munich, Germany   Phone: +49(89)218077680   Email: Paul.Knochel@cup.uni-muenchen.de
,
Romain Blanc
Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5‒13, 81377 Munich, Germany   Phone: +49(89)218077680   Email: Paul.Knochel@cup.uni-muenchen.de
,
Elodie Sansiaume-Dagousset
Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5‒13, 81377 Munich, Germany   Phone: +49(89)218077680   Email: Paul.Knochel@cup.uni-muenchen.de
,
Paul Knochel*
Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5‒13, 81377 Munich, Germany   Phone: +49(89)218077680   Email: Paul.Knochel@cup.uni-muenchen.de
› Author Affiliations
Further Information

Publication History

Received: 05 May 2014

Accepted after revision: 07 May 2014

Publication Date:
30 October 2014 (online)


Abstract

An overview of the most significant synthetic methods currently available for the preparation of functionalized organo­metallic compounds starting from organic halides is presented and illustrated with recent applications.

1 Introduction

2 Metal Insertion

2.1 Magnesium

2.2 Aluminum

2.3 Zinc

2.4 Indium

2.5 Manganese

3 Halogen‒Metal Exchange

3.1 Lithium

3.2 Magnesium

3.3 Zinc

4 Conclusion

 
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