Rhodium(III)-Catalyzed ortho-C–H Alkylation of 2-Arylbenzothiazoles and 2-Arylthiazoles with Potassium Alkyltrifluoroborates

Abstract

A general and efficient Rh(III)-catalyzed ortho-C–H alkylation of 2-arylbenzothizazoles and 2-arylthiazoles with potassium alkyltri­fluoroborates has been developed. The present method leads to the construction of a library of alkylated 2-arylbenzothiazoles and 2-arylthiazoles with yields up to 99%.

Key words

alkylation - alkyltrifluoroborates - 2-arylbenzothiazoles - 2-arylthiazoles - transition metal

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