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Synthesis 2017; 49(17): 3931-3936
DOI: 10.1055/s-0036-1589010
DOI: 10.1055/s-0036-1589010
special topic
Cobalt-Catalyzed Monoselective ortho-C–H Ethylation of Carboxamides with Triethylaluminum
We are grateful to the Natural Science Foundation of China (21602119, U1504208), and for financial support from He’nan Provincial Department of Science and Technology (152300410117).Further Information
Publication History
Received: 15 February 2017
Accepted after revision: 30 March 2017
Publication Date:
29 May 2017 (online)
Published as part of the Special Topic Cobalt in Organic Synthesis
Abstract
A 1,10-phenanthroline ligated cobalt catalyst is reported for the ortho-C–H ethylation of aromatic, heteroaromatic, and alkenyl carboxamides with inexpensive triethylaluminum. This reaction represented the first example of cobalt-catalyzed monoselective direct ortho-C–H ethylation reaction with aluminum reagent as an alkyl donor.
Supporting Information
- Supporting information for this article is available online at https://doi.org /10.1055/s-0036-1589010.
- Supporting Information
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