Non-stabilized pyridinium methylides were successfully generated
from N-(siliymethyl)pyridone analogs
via 1,4-silatropy and the resulting 1,3-dipoles were trapped by
reaction with acetylenic and olefinic dipolarophiles to afford N-heteropolycycles.
The method does not require the use of any additives or strong bases.
1,3-dipolar cycloaddition - 1,4-silatropy - pyridinium methylides - pyridone analogs
- N-heterocycles