Addition of Trialkylalanes to Imines under Zirconium Catalysis

Abstract

Trialkylalanes, which are inert toward imines, undergo addition to them in the presence of a catalytic amount of dichloro­dicyclopentadienylzirconium(IV) (Cp₂ZrCl₂). The reaction tolerates the presence of several functional groups in the starting imine such as halo, amide, nitrile, and hydroxy groups. A possible reaction pathway is proposed involving metallacyclic intermediates.

zirconium - catalysis - trialkylalanes - amine synthesis - imines

References

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