Abstract
The hallucinogenic mushroom Inocybe aeruginascens contains several typical Psilocybe alkaloids including psilocybin. We have now elucidated the structure of a further
indole derivative named aeruginascin as the quaternary ammonium compound N,N,N-trimethyl-4-phosphoryloxytryptamine. Aeruginascin is closely related to the frog
skin toxin bufotenidine (5-HTQ), a potent 5-HT3 receptor agonist, and has been found exclusively in Inocybe aeruginascens so far.
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Prof. Dr. Hartmut Laatsch
Institute of Organic and Biomolecular Chemistry
Georg-August University Göttingen
Tammannstrasse 2
37077 Göttingen
Germany
Phone: +49-551-39-3211
Fax: +49-551-39-9660
Email: hlaatsc@gwdg.de