A Novel Reaction of 4-(Arylmethylene)-2-phenyloxazol-5(4H)-ones with Pyridin-2-amine: Formation of 3-(Arylmethyl)-3-(benzoylamino)imidazo-[1,2-a]pyridin-2(3H)-ones

Shujiang Tu; Junyong Zhang; Runhong Jia; Yan Zhang; Bo Jiang; Feng Shi

doi:10.1055/s-2007-965898

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A Novel Reaction of 4-(Arylmethylene)-2-phenyloxazol-5(4H)-ones with Pyridin-2-amine: Formation of 3-(Arylmethyl)-3-(benzoylamino)imidazo-[1,2-a]pyridin-2(3H)-ones

Shujiang Tu*, Junyong Zhang, Runhong Jia, Yan Zhang, Bo Jiang, Feng Shi
Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plant, Xuzhou, Jiangsu, 221116, P. R. of China
Fax: +86(516)83403164; e-Mail: laotu@xznu.edu.cn;

Abstract

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Abstract

A new series of imidazo[1,2-a]pyridin-2-one derivatives were synthesized by a novel reaction of 4-(arylmethylene)-2-phenyloxazol-5(4H)-one with pyridin-2-amine under microwave irradiation in ethylene glycol. The starting materials were easily obtained and the operation was convenient.

Key words

heterocycles - microwave irradiation - 4-(arylmethylene)-2-phenyloxazol-5(4H)-ones - 3-(arylmethyl)-3-(benzoylamino)imidazo[1,2-a]pyridin-2(3H)-ones - cascade reaction

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References

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