Planta Med 1972; 22(7): 306-315
DOI: 10.1055/s-0028-1099614
© Georg Thieme Verlag Stuttgart · New York

CHEMIE UND WIRKUNGSMECHANISMUS DES COLCHICINS UND SEINER DERIVATE

D. Werner, K. H. Dönges
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Publication History

Publication Date:
15 January 2009 (online)

Abstract

A survey is given about chemistry and effect mechanism of colchicine and its derivatives, which have antimitotic efficiency and are used against tumor. It is assumed that the effect of colchicine is conditioned by special molecular structure. Also the different effect of the variable derivatives depends on the distribution between medium and cell.

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