Download PDF
Synthesis 1985; 1985(11): 1043-1047
DOI: 10.1055/s-1985-31423
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of 3-Ethoxycarbonyl-3-buten-4-olides and 3-Ethoxycarbonyl-4-butanolides

Françoise Gaudemar-Bardone* , Margarita Mladenova, RENÉ. Couffignal
  • *Université Pierre et Marie Curie, Laboratoire de Synthèse Organométallique, Bâtiment F, 4 Place Jussieu, F-75 230 Paris Cedex 05, France
Further Information

Publication History

Publication Date:
27 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

This paper describes a synthesis of 3-acyl-2-alkyl-3-ethoxycarbonylpropanoic acids from ethyl 2-oxoalkanoates and 2-bromoalkanoic acids. These acids are cyclised via intramolecular dehydration to give 2,4-dialkyl-3-ethoxycarbonyl-3-buten-4-olides or are condensed with allylzinc reagents to give the 4-alkenyl-2,4-dialkyl-3-ethoxycarbonyl-4-butanolides.

      >