Synthesis 1989; 1989(4): 265-268
DOI: 10.1055/s-1989-27218
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Esters of Lipophilic Proline Analogs by Reduction of Ethyl 5,6- Dihydro-4H-1,2-oxazine-3-carboxylates

Rainer Henning* , Ulrich Lerch, Hansjörg Urbach
  • *Hoechst AG, Postfach 80 03 20, D-6230 Frankfurt/Main 80, Federal Republic of Germany
Further Information

Publication History

Publication Date:
17 September 2002 (online)

Ethyl esters of proline substituted with lipophilic residues in 4- and/or 5-position are obtained via catalytic hydrogenation of the corresponding ethyl 5,6-dihydro-4H-1,2-oxazine-3-carboxylates.

    >