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Synlett 1991; 1991(6): 443-444
DOI: 10.1055/s-1991-20758
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A New Chemoenzymatic Enantioselective Synthesis of Optically Active Benzothiopyran and Benzothiazepin Ring System

Suneel Y. Dike* , Dilip H. Ner, Ashok Kumar
  • *Alchemie Research Centre, P.O.Box 155, Thane-Belapur Road, Thane 400 601, Maharashtra, India
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Publication Date:
07 March 2002 (online)

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A simple enantiocontrolled synthesis of (R)-2-methyl-2,3-dihydro-4H-[1]benzothiopyran-4-one and (R)-2-methyl-2,3-dihydro-1,5 -benzothiazepin-4(5H)-one starting from ethyl (S)-3-hydroxybutyrate is described.

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