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Synthesis 1991; 1991(10): 879-881
DOI: 10.1055/s-1991-26598
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Hydroborations: A New Convenient Route for the Preparation of 4-Alkyl- (or 4-Aryl)chroman-3-ones from 4-Alkyl- (or 4-Aryl)-2H-chromenes

B. S. Kirkiacharian* , A. Danan, P. G. Koutsourakis
  • *Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie de Paris-sud, 5 rue J. B. Clément, F-92 96 Châtenay-Malabry, Cedex, France
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Publication Date:
29 April 2002 (online)

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Hydroboration followed by pyridinium chlorochromate oxidation of 4-alkyl- and 4-aryl-2H-chromenes [4-alkyl- and 4-aryl-(2H)-1-benzopyrans] lead to the corresponding 4-substituted chroman-3-ones [4-substituted (2H)-1-benzopyran-3(4H)-ones] in good yields.

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