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Synlett 1995; 1995(7): 770-772
DOI: 10.1055/s-1995-5062
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The Synthesis of a Synthetic Receptor via Directed Lithiations of Dibenzofuran and Bibenzothiophene

Heather Tye, Colin Eldred, Martin Wills*
  • *School of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK
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Publication History

Publication Date:
31 December 2000 (online)

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Sequential use of three ortho lithiation procedures has been used to construct a variety of potential host compounds in a highly regiospecific manner. An intramolecular displacement of a t-butoxycarbamate protecting group under basic conditions was utilised as a key step in the formation of six membered cyclic urethanes in the synthesis.

Receptor - Host - Lithiation - Dibenzofuran - Dibenzothiophene

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