Planta Med 2006; 72(12): 1165-1167
DOI: 10.1055/s-2006-947238
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Diarylbutyrolactone Lignans from Linum corymbulosum in vitro Cultures

Abdolali Mohagheghzadeh1 , 2 , Thomas J. Schmidt3 , Ürün Bayindir2 , Elisabeth Fuss2 , Iraj Mehregan1 , A. Wilhelm Alfermann2
  • 1Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Research Centre, Shiraz University of Medical Sciences and Health Services, Shiraz, I. R. Iran
  • 2Institut für Entwicklungs- und Molekularbiologie der Pflanzen, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
  • 3Institut für Pharmazeutische Biologie und Phytochemie, Universität Münster, Münster, Germany
In memory of Professor Ernst Reinhard
Further Information

Publication History

Received: April 13, 2006

Accepted: June 27, 2006

Publication Date:
18 September 2006 (online)

Abstract

The arylbutyrolactone lignans (-)-hinokinin, 3,4 : 3′,4′-bis(methylenedioxy)-lign-7(E)-en-9,9′-olide and 3,4 : 3′,4′-bis(methylenedioxy)-lign-7(Z)-en-9,9′-olide, hitherto unknown for the genus Linum, were isolated by HPLC from callus cultures of Linum corymbulosum (Linaceae) and identified by spectroscopic methods.

References

  • 1 Heywood V H. Flowering plants of the world. London; Croomhelm 1985: p 207-8
  • 2 Hegnauer R. Chemotaxonomie der Pflanzen. Vol. 3 and following volumes Basel; Birkhäuser 1964
  • 3 Petersen M, Alfermann A W. The production of cytotoxic lignans by plant cell cultures.  Appl Microbiol Biotechnol. 2001;  55 135-42
  • 4 Mohagheghzadeh A, Hemmati S, Mehregan I, Alfermann A W. Linum persicum: Lignans and placing in Linaceae.  Phytochem Rev. 2003;  2 363-9
  • 5 Sharifnia F, Assadi M. Linaceae. In: Assadi M, Khatamsaz M, Maassoumi AA, editors Flora of Iran No. 34. Tehran; Institute of Forests and Rangelands 2001: p 1-48
  • 6 Rechinger K H. Linaceae. In: Rechinger KH, editor Flora Iranica, issue 106. Graz; Akademische Druck- u. Verlagsanstalt 1974: p 1-20
  • 7 Ayres D C, Loike J D. Lignans: chemical, biological and clinical properties. Cambridge; Cambridge University Press 1990
  • 8 Chang S, Wang D, Wu C, Shiah S, Kuo Y, Chang C. Cytotoxicity of extractives from Taiwania cryptomerioides heartwood.  Phytochemistry. 2000;  55 227-32
  • 9 Buckingham J. Dictionary of Natural Products. London; Chapman and Hall 1994
  • 10 Shieh H, Cordell G A, Lankin D C, Lotter H. The liquid, solid and molecular force field calculated conformations of savinin.  J Org Chem. 1990;  55 5139-45
  • 11 Rajasekhar D, Subbaraju G V, Ravikumar K, Chandramohn K. Justicia lignans V. three new β-apolignans from Justicia neesii Ramamoorthy.  Tetrahedron. 1998;  54 13 227-36
  • 12 Fang J, Lee C, Cheng Y. Lignans from leaves of Juniperus chinensis .  Phytochemistry. 1992;  31 3659-61
  • 13 Banerji J, Das B, Chatterjee A, Snoolery J N. Gadain, a lignan from Jatropha gossypifolia .  Phytochemistry. 1984;  23 2323-7
  • 14 Murashige T, Skoog F. A revised medium for rapid growth and bioassays with tobacco tissue cultures.  Physiol Plant. 1962;  15 473-9
  • 15 Hooykass P JJ, Klapwijk P M, Nuti M P, Schilperoot R A, Rörsch A. Transfer of the A. tumefaciens Ti plasmid to avirulent agrobacteria and Rhizobium ex planta.  J Gen Microbiol. 1977;  98 477-84
  • 16 Gamborg O L, Miller R A, Ojima K. Nutrient requirments of suspension cultures of soybean root cells.  Exp Cell Res. 1968;  50 151-8
  • 17 Lloyd G, McCown B. Commercially-feasible micropropagation of mountain laurel, Kalmia latifolia, by use of shoot-tipp culture.  Int Plant Prop Soc Proc. 1980;  30 421-7
  • 18 Lopes L MX, Yoshida M, Gottlieb O R. Dibenzylbutyrolactone lignans from Virola sebifera .  Phytochemistry. 1983;  22 1516-8
  • 19 Ikeda R, Nagao T, Okabe H, Nakano Y, Matsunaga H, Katano M. et al . Antiproliferative constituents in Umbelliferae plants. IV. Constituents in the fruits of Anthriscus sylvestris Hoffin.  Chem Pharm Bull. 1998;  46 875-8

Prof. Dr. A. Wilhelm Alfermann

Institut für Entwicklungs- und Molekularbiologie der Pflanzen

Heinrich-Heine-Universität Düsseldorf

Universitätsstr. 1

Geb. 26.13

40225 Düsseldorf

Germany

Phone: +49-211-8114603

Fax: +49-211-8111466

Email: alferman@rz.uni-duesseldorf.de

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