Citracridone-I: A New Antispasmodic from Root Barks of Citrus depressa

Meei-Shieu Yang; Tian-Shung Wu; Chao-Hsiung Wang

doi:10.1055/s-2006-962657

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Planta Med 1987; 53(2): 143-147
DOI: 10.1055/s-2006-962657

Full Papers

Citracridone-I: A New Antispasmodic from Root Barks of Citrus depressa

Meei-Shieu Yang¹ , Tian-Shung Wu² , Chao-Hsiung Wang³

¹Department of Pharmacology, Chia Nan Junior College of Pharmacy, Jen-Te Hsiang, Tainan, Taiwan 71710, Republic of China.
²Department of Applied Chemistry, Providence College of Arts and Science, Taichung, Republic of China.
³Department of Chemistry, Chia Nan Junior College of Pharmacy, Tainan, Republic of China.

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Publication History

1986

Publication Date:
24 January 2007 (online)

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Abstract

Citracridone-I (Citra-I), a new acridone alkaloid from the root barks of Citrus depressa, was examined to evaluate toxicity in mice as well as blood pressure and small intestinal propulsion of rats in vivo. The antispasmodic effects of Citra-I were also investigated in the isolated ileum and vas deferens of guinea pig as well as uterine muscle of rat.