Planta Med 1986; 52(6): 490-492
DOI: 10.1055/s-2007-969263
Communications

© Georg Thieme Verlag Stuttgart · New York

Isolation and Hypoglycemie Activity of Oryzarans A, B, C, and D: Glycans of Oryza sativa Roots1

Hiroshi Hikino, Miki Murakami, Yoshiteru Oshima, Chohachi Konno
  • Pharmaceutical Institute, Tohoku University, Aoba-yama, Sendai, Japan.
1 Antidiabetes drugs, Part 24. Also Part 114 in the validity of the Oriental medicines.
Further Information

Publication History

1986

Publication Date:
26 February 2007 (online)

Abstract

A water extract of the Oriental crude drug “tōkon”, the roots of Oryza sativa, noticeably reduced blood sugar concentration in mice. The extract was fractionated by monitoring the activity to yield four glycans, oryzarans A, B, C, and D which remarkably lowered blood sugar level in normal and alloxan-produced diabetic mice.

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