Reductive Electrochemical HPLC Assay for Artemisinin (Qinghaosu)

Nancy Acton; Daniel L. Klayman; Irvin J. Rollman

doi:10.1055/s-2007-969545

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Planta Med 1985; 51(5): 445-446
DOI: 10.1055/s-2007-969545

Reports

Reductive Electrochemical HPLC Assay for Artemisinin (Qinghaosu)

Nancy Acton, Daniel L. Klayman, Irvin J. Rollman

Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Washington, DC 20307-5100, USA

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Publication History

1985

1985

Publication Date:
26 February 2007 (online)

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Abstract

Artemisinin (qinghaosu), a sesquiterpene lactone containing a peroxide bridge, is the known antimalarial constituent of the herb Artemisia annua L. An electrochemical HPLC detection procedure has been developed that provides a sensitive, selective, and rapid assay for artemisinin in crude plant extracts.

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